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Dr. Patrick Walsh

Associate Professor (Clinical Medicine)

 


  Immunology, Immunotherapy   Medicine
 Targetting the IL-36 pathway in IBD

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Details Date From Date To
International Cytokine Society 2018
Faculty member of F1000 Biology 2012
Irish Society of Immunology 2008
British Society of Immunology 2008
Narros-Fernández P, Chomanahalli Basavarajappa S, Walsh PT., Interleukin-1 family cytokines at the crossroads of microbiome regulation in barrier health and disease., The FEBS journal, 2023, Journal Article, PUBLISHED  DOI
Rehill AM, Leon G, McCluskey S, Schoen I, Hernandez-Santana Y, Annett S, Klavina P, Robson T, Curtis AM, Renné T, Hussey S, O'Donnell JS, Walsh PT, Preston RJS., Glycolytic reprogramming fuels myeloid cell-driven hypercoagulability., Journal of thrombosis and haemostasis : JTH, 2023, pS1538-7836(23)00774-2 , Journal Article, PUBLISHED  DOI
Leon, G. Hernandez-Santana, Y.E., Irwin, N., Giannoudaki, E., O'Neill, S., Czismadia, I., Gogarty, M., Lee, T.J., Ruane, D., Long, A., Fallon, P.G., Hussey, S. Walsh, P.T. , IL-36 cytokines imprint a colitogenic phenotype on CD4+ T helper cells., Mucosal Immunology, 2022, Journal Article, PUBLISHED  TARA - Full Text
Brennan, K, Craven, S., Cheung, M, Kane, D., Noone, E., O'Callaghan, J., Molloy, E.J., Walsh, P.T., McAuliffe, F.,Doyle, S.L. , Cytosolic dsRNA improves neonatal innate immune responses to adjuvants in use in paediatric vaccines., Journal of Leukocyte Biology, 2022, Journal Article, PUBLISHED  TARA - Full Text  DOI
Matarazzo, L. and Hernandez Santana, Y.E. and Walsh, P.T. and Fallon, P.G., The IL-1 cytokine family as custodians of barrier immunity, Cytokine, 154, (155890), 2022, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Hernandez Santana YE, Irwin N, Walsh PT., IL-36: a therapeutic target for ulcerative colitis?, Expert opinion on therapeutic targets, 26, (6), 2022, p507-512 , Journal Article, PUBLISHED  DOI
Sullivan, G.P. and Davidovich, P. and Muñoz-Wolf, N. and Ward, R.W. and Hernandez Santana, Y.E. and Clancy, D.M. and Gorman, A. and Najda, Z. and Turk, B. and Walsh, P.T. and Lavelle, E.C. and Martin, S.J., Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement, Science immunology, 7, (78), 2022, peade5728 , Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Bone R, Fennell BJ, Tam A, Sheldon R, Nocka K, Varghese S, Chang CS, Hawerkamp HC, Yeow A, Saunders SP, Hams E, Walsh PT, Cunningham O, Fallon PG, Discovery and multi-parametric optimization of a high-affinity antibody against Interleukin-25 with neutralizing activity in a mouse model of skin inflammation. , Antibody Therapeutics, 29, 2022, p258 - 267, Journal Article, PUBLISHED
Leon G, Hussey S, Walsh PT., The Diverse Roles of the IL-36 Family in Gastrointestinal Inflammation and Resolution., Inflammatory bowel diseases, 27, (3), 2021, p440-450 , Journal Article, PUBLISHED  DOI
Giannoudaki E, Gargan S, Hussey S, Long A, Walsh PT., Opportunities to Target T Cell Trafficking in Pediatric Inflammatory Bowel Disease., Frontiers in pediatrics, 9, 2021, p640497 , Journal Article, PUBLISHED  DOI
  

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Patrick Walsh, The role of the IL-1 family of cytokines as mediators of Inflammatory Disease, 2019, TCD and Royal Irish Academy, (1), 49, European Journal of Immunology, 8-10, Meetings /Conferences Organised, PUBLISHED

  

Award Date
President of Ireland Young Researcher Award SFI 2011-16
Faculty member F1000 Biology 2011
Recipient of GlaxoSmithKline, R&D Exceptional Science Award 2008
Marie Curie Fellow 2009-2013
American Society Of Transplantation Council's Fellowship 2004-2006,
Irish Refining PLC Full University Scholarship, 1997