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Professor John Russell

Clinical Associate Professor (Paediatrics)
      
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Professor John Russell

Clinical Associate Professor (Paediatrics)

 russelj1@tcd.ie

 


I have been a consultant practicing the sub-speciality of Paediatric Otorhinolaryngology since 1996 having completed my Paediatric fellowship in Great Ormond Street Hospital, London, UK in 1995. Since that time I have been actively involved in teaching and training medical students, nurses, GP's and ENT trainees at all levels. In 2002 I became the first Programme Director in Otorhinolaryngology and Head & Neck Surgery at the Royal College of Surgeons in Ireland (R.C.S.I) I was responsible for overseeing the training of 23 trainees and organising the annual Senior Academic Council (S.A.C) representative visits along with organising mock intercollegiate examinations until 2006. It was very satisfying to have been a supervisor to a BSc, MSc and a PhD student. My translational research commenced in 1986 with studies of the rat tympanic membrane in persistent middle ear effusion at University College Dublin (U.C.D) and continued up until 2004. In 2006 I started research in the area of subglottic stenosis at U.C.D and at The National Children's Research Centre (N.C.R.C) at Crumlin. This research is ongoing and looking into wound healing mediators. Apart from being the Programme Director, I was appointed Secretary to the Irish Institute of Otorhinolaryngology and Head and Neck Surgery(I.I.O.H.N.S) in Ireland from 2004 to 2007. In 2010, I was elected to the board of the European Society of Pediatric Otorhinolaryngology (E.S.P.O)and in 2014 I became the President of E.S.P.O for a two year term. In 2015,I was voted to the position of General-Secretary of the Presidential Council of the Confederation of European Otorhinolaryngology-Head and Neck Surgery (CEORL-HNS). The CEORL-HNS is the representative body for all Otolaryngology/Head and Neck Surgery in Europe. One of my biggest educational achievements, I think, was to organise the bienniel European Society of Paediatric Otorhinolaryngology (E.S.P.O) Congress which took place in Dublin in 2014 and was attended by 1200 international delegates. In June 2019, I was successful in bidding to organise, host and be the Congress President for the Seventh Congress of the CEORL-HNS to be held in the Convention Centre in Dublin in 2024. In March 2022 I became an Associate Editor for the International Journal Of Pediatric Otorhinolaryngology (IJPORL) In June 2024 I organised and was the Congress President for the Seventh Congress of the Confederation Of European Otorhinolaryngology- Head and Neck Surgery held in Dublin (June 15th to 19th) at the Convention Centre. There were 3400 delegates from over 60 countries with 16 parallel sessions for the duration of the congress.
Project Title
 Investigation into prevention of fibrotic scar formation as treatment for Subglottic Stenosis
From
1/10/2019
To
30/9/2022
Summary
Subglottic stenosis (SGS) is a serious condition where the area beneath the vocal cords becomes narrowed due to a buildup of fibrotic tissue (scarring). It commonly results after intubation in premature babies. The ability to modify this excessive scar/fibrotic tissue is an ideal objective in the management of SGS. Treatment of SGS currently involves surgical techniques, which in turn carry a risk of re-scarring (restenosis). Several treatments have been used in an attempt to minimize scarring with limited success. There is a critical need to develop therapies to treat scarring to improve outcomes for children with SCS. The overall objective of this study is to develop a novel drug treatment for SGS. Previous research has led to the identification of a molecule termed BMP3. Our preliminary research indicts that BMP3 could prevent scarring in the airway. Our objective is to test BMP3 as a drug using laboratory based models. We will investigate if BMP3 is lost in the airway following the intubation. We will also test treatment with BMP3 to prevent scarring. These studies will establish if we can use BMP3 to prevent scar formation and stop SGS. By better understanding the processes that contribute to how preterm babies develop SGS we will be able to develop more effective treatments. The long-term goal is to develop BMP3-based therapy that could prevent scarring. This work has the potential to impact all children that undergo intubation, who are at risk from associated scarring. A therapy that would slow or prevent scarring would significantly benefit child health. Scarring is a contributing factor to many diseases including lung fibrosis and arthritis. BMP3 treatment could potentially improve quality of life and protect against fatalities, with scope far beyond SGS.
Funding Agency
National Children's Research Centre (NCRC)
Programme
Basic, Clinical and Translational Research
Project Type
Post Doctoral Research
Person Months
48
Project Title
 Optimising the Use of Mitomycin C in Subglottic Stenosis
From
2009
To
2012
Summary
Funding Agency
National Children's Research Centre (NCRC)
Project Type
PhD
Person Months
36

Details Date
I was Chairman and Congress President of the Local and International ,Organising and Scientific Committees for the 12th International Congress of the 2014 European Society of Pediatric Otorhiniolaryngology (ESPO) Dublin, June 2014. 2010
I was Chairman and President of the Board of the European Society of Pediatric Otorhinolaryngology (ESPO) 2014
Reviewer for the Journal Folia Phoniatrica et Logopaedica 1996
Reviewer for the International Journal of Pediatric Otorhinolaryngology 2005
Reviewer for the European Archives of Otorhinolaryngology 2017
Reviewer for C Surgeries 2105
I represented the specialty Of Otorhinolaryngology-Head and Neck surgery on the Professional Competence committee of the Royal College of Surgeons in Ireland 2010
Associate Editor of International Journal Of Paediatric Otorhinolaryngology 20/4/2022
Represented the Speciality of Otorhinolaryngology-Head and Neck Surgery on behalf of the Royal College of Surgeons in Ireland .This was a request by HIQA for advice regarding National Guidelines for common ENT operations such as Tonsillectomy, Grommets and Adenoidectomy 2015
Treasurer of the European Society of Pediatric Otorhinolaryngology(ESPO) 2016
Presidential Council Member of the Confederation of Otorhinolaryngology-Head Neck Surgery (CEORL-HNS) 2015
Secretary-General of the Confederation of the European otorhinolaryngology-Head and Neck Surgery (CEORL-HNS) 2017
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Details Date From Date To
Fellow of the Royal College of Surgeons of Ireland 1994 present day
Irish Institute of Otorhinolaryngology-Head Neck surgery 2000 present day
International Member of the American Society of Pediatric Otorhinolaryngology (ASPO) 2012 present day
Board Member of the European Society of Pediatric Otorhinolaryngology(ESPO) 2010 2021
President of the European Society of Pediatric Otorhinolaryngology (ESPO) 2014 2016
Treasurer of the European Society of Pediatric Otorhinolaryngology(ESPO) 2016 2021
Presidential Council Member of the Confederation of Otorhinolaryngology-Head Neck Surgery (CEORL-HNS) 2015 2024
Secretary-General of the Confederation of Otorhinolaryngology -Head and Neck Society(CEORL-HNS) 2017 2019
Airway Disorders: Subglottic Stenosis in, editor(s)Losty P D,Corbally T D , Essential Paediatric Surgery: A Practical Guide, Boca Ratan, CRC Press, 2024, [Lang B,Mehanna R, Russell J.], Book Chapter, PUBLISHED
Ryan PJ, Casby C, Russell J, Holt F., Stridor and severe subglottic stenosis: emergency tracheostomy for a neonate with a pinhole trachea., BMJ case reports, 17, (6), 2024, pe259901 , Journal Article, PUBLISHED  DOI
Dorris ER, Phelan DE, Russell J, Murphy M., Bone morphogenetic protein-3 is a negative regulator of transforming growth factor beta and fibrosis., Biochemical and biophysical research communications, 738, 2024, p150497 , Journal Article, PUBLISHED  DOI
Aldriweesh B, Alkhateeb A, Boudewyns A, Chan CY, Chun RH, El-Hakim HG, Fayoux P, Gerber ME, Kanotra S, Kaspy K, Kubba H, Lambert EM, Luscan R, Parikh SR, Rahbar R, Rickert SM, Russell J, Rutter M, Schroeder JW, Schwarz Y, Sobol SE, Thevasagayam R, Thierry B, Thompson DM, Valika T, Watters K, Wei JL, Wyatt M, Zur KB, Daniel SJ., International pediatric otolaryngology group (IPOG) consensus on approach to aspiration., International journal of pediatric otorhinolaryngology, 176, 2024, p111810 , Journal Article, PUBLISHED  DOI
de Blacam Catherin, Butler Dary, Duggan Laur, Byrne Sandr, Russell Joh, Javadpour Sheil, White Marti, Orr David JA, Minimally-invasive airway management and early cleft palate repair in infants born with robin sequence, Journal of Cranio-Maxillofacial Surgery, 2024, Journal Article, PUBLISHED  DOI  URL
Case Study 7-1: Use of a modifiied Speaking Valve in an Infant in, editor(s)Diez Gross R,King K A , Tracheostomy and Ventilator Dependence in Adults and Children, San Diego USA, Plural Publishing, 2023, [Greene Z, Fitzgerald S,Prudente R,Harnett P,Russell J.], Book Chapter, PUBLISHED
Tracheostomy in, editor(s)Hollwarth ME, Puri P. , Pediatric Surgery: Diagnosis and Management, New York, Springer, 2023, [Woods L,Lobe T E,Russell J.], Book Chapter, PUBLISHED
Choanal Atresia in, editor(s)Hollwarth ME,Puri P. , Pediatric Surgery:Diagnosis and Management, New York, Springer, 2023, [Speaker R B, Harney M, Russell J.], Book Chapter, PUBLISHED
Schiff E, Propst EJ, Balakrishnan K, Balakrishnan K, Johnson K, Lounsbury DW, Brenner MJ, Tawfik MM, Pediatric Tracheostomy Emergency Readiness Workgroup, Yang CJ., Pediatric Tracheostomy Emergency Readiness Assessment Tool: International Consensus Recommendations., The Laryngoscope, 133, (12), 2023, p3588-3601 , Journal Article, PUBLISHED  DOI
Roy CF, Balakrishnan K, Boudewyns A, Cheng A, Chun RH, Daniel SJ, Fayoux P, Hart C, Hemansson A, Hewitt R, Hsu WC, Kuo M, Liu C, Maddalozzo J, Messner AH, Pransky S, Rahbar R, Rickert S, Roy S, Russell J, Rutter MJ, Sie KCY, Sidell D, Smith R, Soma M, Spratley J, Watters K, White DR, Wolter N, Zalzal G, Yeung JC., International Pediatric Otolaryngology Group: Consensus guidelines on the diagnosis and management of non-tuberculous mycobacterial cervicofacial lymphadenitis., International journal of pediatric otorhinolaryngology, 166, 2023, p111469 , Journal Article, PUBLISHED  DOI
  

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John Russell, Supraglottic/Glottic/Subglottic/Tracheal Stenosis/Moderator, European Laryngological Society Annual Meeting, Virtual, 5th June , 2020, Professor Christian Sittel , Notes: [I organised and moderated this Hour long presentation Key speakers Professor Michael Rutter ,Cinncinnati, USA.Professor Steven Sobel ,Philadelphia, USA Professor Faruk Unal ,Istanbul,Turkey.Professor Vincent Couloigner,Paris ,France .], Invited Talk, PRESENTED
John Russell, Branchial Csyts, Sinuses and Fistulaes , Webinar for British Association of Paediatric Otolaryngology (BAPO), Virtual, 19th May, 2020, Mr Michael Kuo Chief of Paediatric Otolaryngology (Birmingham) , Invited Talk, PRESENTED
John Russell, Resorbable Minipalates and Laryngotracheal surgery, International Airway Dialogues Meeting , Paris ,France , June , 2019, Professor Francoise Denoyelle ,Mr David Albert ,Mr Michael Kuo, Invited Talk, PRESENTED
John Russell, Complications Of Laryngotracheal Surgery , 21st Paediatric Otolaryngology Days, Poznan ,Poland, May , 2019, Professor Jarek Szydlowski, Invited Talk, PRESENTED
John Russell, Laryngomalacia, 2nd Paediatric Paediatric Otorhinolaryngological conference, Sofia , Bulgaria, February, 2019, Professor Dilyana Vicheva, Invited Talk, PRESENTED
John Russell, Update on Otitis Media with Effusion, Annual Belgian Otorhinolaryngology meeting , Antwerp,Belgium , November , 2018, Professor An Boudewyns, Invited Talk, PRESENTED
John Russell, How to Avoid mistakes in Laryngotracheal Reconstruction , The 14th Congress of the European Society of Pediatric Otorhinolaryngology (ESPO), Stockholm, June, 2018, Professor Ann Hermansson, Invited Talk, PRESENTED
John Russell, Paediatric Airway:Advances in Anaesthesia and Paediatric Intensive Care , 4th Congress of the Confederation of European otorhinolaryngology-Head and Neck Surgery(CEORL-HNS), Barcelona ,Spain , October , 2017, Professor Ferhan Oz and (CEORL-HNS), Invited Talk, PRESENTED
A Snow, Paediatric MRA/MRV, Irish MRI Meeting, Kilkenny, January, 2017, Invited Talk, PUBLISHED
John Russell, Update on Paediatric ENT , ENT Update ,Europe , Vienna ,Austria , September , 2016, Professor Hans Eckel , Invited Talk, PRESENTED

  


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Award Date
Honours in Surgery June 1984
Honours in Bsc Anatomy June 1986
Weill Cornell University New York ,USA. Visiting Professor and Guest Lecturer April 2011
Invited Guest Lecturer and Tutor .International Course on SubGlottic Stenosis, Stuttgart,Germany February 2016
Invited Guest Lecturer to give the Annual "John Evans Lecture"at the Annual British Association of Paediatric Otolaryngology(BAPO) meeting in Birmingham UK 23rd September 2021
2024 Visiting Professor to Boston Children's Hospital/ Harvard Medical Schoool 3-4th April 2024
Visiting Professor to Carolina's Airway Course , North Carolina / University of North Carolina UNC 9/3/2023 - 10/3/2023
There are 2 very important diseases in Paediatric Otorhinolaryngology(ENT) Otitis Media with Effusion(OME)the commonest disease of childhood after the common cold and acquired Sub-Glottic Stenosis which cuases significant morbidity particularly to premature babies. Since 1985 these 2 Topics have been my main Research focus. In 1985 I began studying the effects of prolonged Otitis Media on the ultrastructure of the Tympanic membrane in an Animal model and continued this research up until 2004.Two major pieces of work achieved included (1)Studies of the Tympanic Membrane in Persistent Middle Ear Effusion,1986. This was part of my BSc in Anatomy degree. (2)The Effects of prolonged Otitis Media with Effusion on the Tympanic Membrane: An Experimental Study in the Rat,2004. This Thesis was carried out for my MCh (Masters of surgery)which I was awarded in 2004 . In 2009 I started studying Sub-Glottic stenosis and have continued this research to the present day. Key achievements so far, (1)Optimising the Use of Mitomycin C in Subglottic Stenosis 2013 This research was a 3 year project For a PhD student under my Co-supervision and was funded by The National Childrens Research Centre(NCRC) and awarded in 2013. (2)MicroRNAs as Novel Theraputic Targets for the Treatment of Subglottic Stenosis,2016. This was an MSc thesis of which I was a Co-supervisor It was awarded in 2016. (3)Investigation into prevention of fibrotic scar formation as treatment for subglottic stenosis.2019-2022. This is a Post Doctoral research project of which I am a co- Principal investigator .Funding Agency National Children's Research Centre (NCRC) The above research has produced a BSc Degree and an MCh degree for myself. I have supervised an MSc and a PhD student who both achieved their respective degrees . I am currently working as a Co-Principal investigator in a post Doctoral research project. All this research has produced 3 significant publications and promoted me to the International stage in the area of Sub-Glottic Stenosis as evidenced by my many invitations as an International speaker ,moderator and Instructor .