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Professor Patrick Prendergast

Research Professor (Mechanical, Manuf & Biomedical Eng)

 


Patrick Prendergast, BA, BAI, PhD, ScD, C.Eng, FIEI, FIAE, FREng, MRIA, SFTCD is an Honorary Principal Investigator in the Trinity Centre for Biomedical Engineering (TCBE). Together with colleagues from Engineering, Medicine and Dentistry, he led the application to establish the TCBE under the Programme for Research in Third-level Institutions (PRTLI). He was the inaugural Director from 2003 to 2008. Dr Prendergast was Professor of Bio-Engineering from 2007 until his appointment as President/Provost required him to relinquish his professorship in 2011. In 2011 he was appointed the 44th President & Provost of Trinity College Dublin and held office for a 10-year term. Prior positions in university administration were Chief Academic Officer & Vice-Provost (2008-2011), and Dean of Graduate Studies (2004-2007). Further details on former Provosts are given at www.tcd.ie/provost/biography/former-provosts/patrick-prendergast-/. On returning to the faculty in 2021, he was appointed as Research Professor in the University. Prior to working in TCD he held post-doctoral positions in Rizzoli Orthopaedic Institute, Bologna and the University of Nijmegen, The Netherlands, where he worked with Prof.dr.ir. Rik Huiskes. On a sabbatical year 2001-2002 he was Visiting Professor, Institute of Fundamental Technological Research, Poland and Senior Research Fellow, Koiter Institute, Technical University of Delft and the Department of Orthopaedics of Erasmus University Rotterdam, The Netherlands. He also did a sabbatical year at the Institute of Bioengineering of UPC, Barcelona, Spain in 2007-2008 working with Professor Josep Planell. His engineering work is in biomechanics, implant analysis and design, and mechanobiology of skeletal tissues. For several decades his publications have appeared in the Elsevier World's Top 2% Scientists Ranking. Graduate Students in Engineering (alphabetical order) Boyle, Colin; PhD; 2011 Britton, John; PhD; 2004 Byrne, Damien; PhD; 2009 Carriero, Allesandra; MS; 2002 Connolly, Paul; MCh; 2000; Co-advisor: Mr J. MacElwaine, FRCSI, Tallaght Hospital Ferris, Peter; MSc; 1998 Flannery, Olivia; MCh; 2007; Co-advisor: Mr J. MacElwaine, FRCSI, Tallaght Hospital Galibarov, Pavel; PhD; 2010; Co-supervisor: Dr Alex Lennon Keeling, Parnell; MCh; 2009; Co-advisor, Mr Paddy Kenny, FRCSI, James Connolly Memorial Hospital Kelly, Daniel; MSc;2001 Kelly, Daniel; PhD; 2004 Kenny, Paddy; MCh; 2003; Co-advisor: Mr J. MacElwaine, FRCSI, Tallaght Hospital Khayyeri, Hanifeh; PhD; 2011 Lacroix, Damien; MSc; 1998 Lacroix, Damien; PhD; 2001 Lally, Catriona; PhD; 2004 Lennon, Alexander; PhD; 2003 Lowrey, Colm; MSc; 2010 MacNicoll, Ruari; MCh; 2008; Co-advisor, Mr Paddy Kenny, FRCSI, James Connolly Memorial Hospital Maher, Suzanne; PhD; 2000 McCormack, Brendan; PhD; 1997; External Supervisor under UCD PhD regulations (Nominating Professor: D.F. Moore) McGarry, James; PhD; 2005; Co-supervisor Prof. Suzi Jarvis, SFI Nanoscience Laboratory McLoughlin, Ruth; MSc; 2008 McMahon, Louise; PhD; 2007; Co-supervisor: Prof. Veronica Campbell, Department of Physiology McNamara, Laoise; PhD; 2004 Moretti, Matteo; MSc; 2001; Co-supervisor: Dr Adrielle Prina-Mello Mulvihill, Brianne; PhD; 2009 Murphy, Bruce; PhD; 2001 Murphy, Linda; PhD; 2002 Nowlan, Niamh; PhD; 2007; Joint supervision with Prof Paula Murphy, Department of Zoology Prina-Mello, Adrielle; PhD; 2003; Co-supervisor: Prof. Y. Volkov, School of Medicine Roddy, Karen; PhD; 2010; Joint supervision with Prof Paula Murphy, Department of Zoology Scannell, Paul; PhD; 2006 Toland, Simon; MSc; 1993; Co-Supervisor Prof David Taylor, Mechanical Engineering Vard, John; MSc; 2004 Waller, Mary; MSc; 2004; Co-supervisor: Prof. Fergal O'Brien, RCSI Walsh, Laura; MSc; 2004 Wulliamoz, Patrick; PhD; 2012 Xue, Feng; PhD; 2014
  ACCUMULATION   ACOUSTICS   ADAPTATION   ALTERED STRAIN ENVIRONMENTS   ALTERNATIVES TO ANIMAL TESTING   ANTHROPLASTY   ARTHRITIS   ARTHROPLASTIES   ARTHROPLASTY   ARTICULAR-CARTILAGE   BAYESIAN ANALYSIS   BEHAVIOR   BIMATERIAL INTERFACE   Bioengineering   BIOLOGICAL TISSUES   BIOMATERIALS   BIOMECHANICS   Biomechanics, Biomedical Engineering   Biomedical Engineering   Biomedical sciences   BIPHASIC ARTICULAR-CARTILAGE   BONE   BONE ADAPTATION   BONE CEMENT   BONE DAMAGE   BONE-CEMENT   CANCELLOUS BONE   CAT EARDRUM   CELL BIOMECHANICS   CELLS   CEMENT   CEMENT TECHNIQUE   COMPACT BONE   COMPONENTS   COMPUTER SIMULATION   CRACKS   DAMAGE   DAMAGE ACCUMULATION   DENSITY   DESIGN   EAR   Energy Release/Transport   Engineering underpinning biomedicine   EPIPHYSEAL-BASED DESIGNS   FAILURE   FATIGUE   FEMORAL STEMS   FEMUR   FINITE ELEMENT ANALYSIS   FINITE ELEMENT MODELS   FINITE ELEMENTS   FIXATION   FRACTURE FIXATION DEVICES   FRACTURE HEALING   FRACTURE MECHANICS   HAND-ACCESS PORT   HEARING   HIP PROSTHESIS   HIP REPLACEMENT   HIP-JOINT   HUMAN TEMPORAL BONES   HYDRATED SOFT-TISSUE   IMPLANT DESIGN   IMPLANT TESTING   IMPLANTS   INDUCIBLE DISPLACEMENT   INTERFACES   INTRAMEDULLARY PLUG   INTRAMEDULLARY PROSTHESES   LOOSENING   LUMBAR MOTION SEGMENT   MECHANISM   MECHANOBIOLOGY   Medical Devices   MESENCHYMAL STEM CELLS   MICROCRACKING   MICROMANUFACTURING   MICROTEXTURED   MIGRATION   MODEL   NANOBIOTECHNOLOGY   OBSTRUCTION   ORTHOPAEDICS   PRE-CLINICAL TEST   PROSTHESES   PROSTHESIS   PROSTHESIS COLLAR   PUSH-OUT TEST   REMODELLING   REPLACEMENT   STABILITY   STANDARDS   STEM   Stem Cell   STRENGTH   STRESS   STRESS-ANALYSIS   STRESSES   SUBSIDENCE   TIBIAL PLATEAU COMPONENTS   Tissue Banks, Engineering   Tissue Engineering   TOTAL HIP-ARTHROPLASTY   TOTAL HIP-REPLACEMENT   TOTAL KNEE REPLACEMENT   TOTAL SHOULDER ARTHROPLASTY
 Computer simulation of biodegradation scaffolds: Validation against experiments and implementation for tissue engineering
 An International Symposium entitled "Innovation: the third pillar of Irish Higher education?"
 Mechanoresponsiveness of mesenchymal stem cells with ageing
 Mechanoregulation of patterning genes during development of the embryonic skeleton: growth and differentiation in the absence of muscle contractions.
 Computational Mechanobiology: fundamental advances and implementation for medical device engineering

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Details Date
President of the European Alliance of Medical and Biological Engineering Societies 2007
Chair, European Society of Biomechanics Workshop on Finite Element Modelling in Biomechanics and Mechanobiology 2007
External Examiner, Mechanical & Systems Engineering, University of Newcastle 2007
Examiner, Dottorato di Ricerca (VIII cycle) Scuola Interpolitecnica di Dottorato (Milano, Torino, Bari) 2006-
President, European Alliance of Medical and Biological Engineering Societies 2007
Guest Editor (with Prof. T.C. Lee) "Micro-damage in Bone", European Journal of Morphology, Vol. 42, Issue Nr. 1/2, 2005 2005
Editorial Board of the Journal of Orthopaedics and Traumatology 2004-
Editorial Board of the Journal of the Royal Society, Interface 2004-
Guest Editor with Prof. R. Contro, "Mechanics of Tissues and Implants", Meccanica Vol.35, Issue Nr. 4/5, 2002 2002
President, European Society of Biomechanics 2002-04
Director, Eblana Photonics, Trinity Enterprise Centre, Pearse St., Dublin, Ireland 2001-
Editorial board of European Cells and Materials (www.ecmjournal.org) 2000-
Chair, 12th Conference of the European Society of Biomechanics 2000
Editorial Board of the Journal of Biomechanics (2001-05 as Book Review Editor; 2005- as Surveys Editor) 1999-
President, Section of Bioengineering, Royal Academy of Medicine in Ireland 1998-00
Editorial Board of Clinical Biomechanics 1994-
Details Date From Date To
Member of the Institution of Engineers of Ireland 1987 -
Member of the European Society of Biomechanics 1990 -
Member of the American Society of Mechanical Engineers 1995 -
Fellow of the Royal Academy of Medicine in Ireland 1995 -
Member of the Biomedical Engineering Society (US) 2003 -
Member of Tissue Engineering Society International 2004 -
Founding Fellow, European Alliance of Biomedical Engineering Societies (EAMBES) 2005
Kelly, D.J. and O'Brien, F.J. and Prendergast, P.J., A Short History of Bioengineering Research in Ireland, Journal of Biomechanical Engineering, 140, (2), 2018, p021005 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Xue, F., Lennon, A.B., McKayed, K.K., Campbell, V.A., Prendergast, P.J., Effect of membrane stiffness and cytoskeletal element density on mechanical stimuli within cells: an analysis of the consequences of ageing in cells, Computer Methods in Biomechanics and Biomedical Engineering, 18, (5), 2015, p468 - 476, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Taylor, M. Prendergast, P.J., Four decades of finite element analysis of orthopaedic devices: Where are we now and what are the opportunities?, Journal of Biomechanics, 48, (5), 2015, p767 - 778, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Khayyeri H, Isaksson H, Prendergast PJ, Corroboration of computational models for mechanoregulated stem cell differentiation., Computer methods in biomechanics and biomedical engineering, 18, (1), 2015, p15-23 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Rolfe,Rebecca A. , Nowlan,Niamh C. , Kenny,Elaine M. , Cormican,Paul , Morris,Derek W. , Prendergast, Patrick J. ., Kelly, Daniel John ., Murphy, P., Identification of mechanosensitive genes during skeletal development: Alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways, BMC Genomics, 15, (1), 2014, p48-, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Khayyeri H, Prendergast PJ, The emergence of mechanoregulated endochondral ossification in evolution., Journal of biomechanics, 46, (4), 2013, p731-7 , Journal Article, PUBLISHED
Boyle CJ, Lennon AB, Prendergast PJ, Application of a mechanobiological simulation technique to stents used clinically., Journal of biomechanics, 46, (5), 2013, p918-24 , Journal Article, PUBLISHED
Newe, C., Cunningham, E., Buchanan, F., Walker, G., Prendergast, P.J., Lennon, A., Dunne, N., Static and dynamic degradation of sintered calcium phosphate ceramics, Key Engineering Materials, 493-494, 2012, p861 - 865, Journal Article, PUBLISHED  DOI
Nowlan, N.C., Dumas, G., Tajbakhsh, S., Prendergast, P.J., Murphy, P., Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis., Biomechanics and Modelling in Mechanobiology, 11, 2012, p207 - 219, Journal Article, PUBLISHED
Galibarov PE, Prendergast PJ, Lennon AB, A probabilistic modelling scheme for analysis of long-term failure of cemented femoral joint replacements., Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 226, (12), 2012, p927-38 , Journal Article, PUBLISHED
  

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Address at Mount Jerome Cemetery on Thomas Davis in, Thomas Davis. A Bi-Centenary Commemorative Journal 1814-2014, Macroom, 2015, pp189 - 193, [Patrick Prendergast], Book Chapter, PUBLISHED
Simulation of in-stent restenosis for the design of cardiovascular stents in, G. Holzpafel & R. Ogden , Mechanics of Biological Tissue, Springer, 2006, pp255 - 267, [Lally, C, Prendergast, PJ], Book Chapter, PUBLISHED
Analysis of joint and muscle loads in, editor(s)Mow, VC, Huiskes, R , Basic Orthopaedic Biomechanics and Mechanobiology, Lippencodt Williams & Wilkins, 2005, [Prendergast, PJ, van der Helm, FCT, Duda, GN], Book Chapter, PUBLISHED
Experiment and computation in mechanobiology, with new applications in cardiology and evolution in, editor(s)J. Piekarski , Tissue Remodelling, Warsaw, Centre of Excellence for Applied Biomedical Modelling and Diagnostics, 2005, pp219 - 240, [Prendergast, PJ, Nowlan, NC, Lally C], Book Chapter, PUBLISHED
Modelling the response of cells to mechanical stimulation in, editor(s)Józef Joachim Telega , Modelling in Biomechanics: Lecture Notes 19 of AMAS (Polish Academy of Sciences), Warsaw, Institute of Fundamental Technological Research, 2005, pp159 - 189, [Prendergast, PJ, Kelly, DJ, McGarry, JG ], Book Chapter, PUBLISHED
Prendergast PJ, McHugh PE (Editors), Topics in Bio-Mechanical Engineering, Dublin, Trinity Centre for Bioengineering & National Centre for Biomedical Engineering Science, 2004, 1 - 249pp, Book, PUBLISHED
Computational mechanobiology in, editor(s)M Cerrolaza, M Doblaré, G Martínez, B Calvo , Computational Bioengineering: Current Trends and Applications, Imperial College Press, 2004, [Prendergast, PJ], Book Chapter, PUBLISHED
Mechanobiology: Experiment and Computation in, editor(s)PJ Prendergast, PE McHugh , Topics in Bio-Mechanical Engineering, Dublin, Trinity Centre for Bioengineering & National Centre for Biomedical Engineering Science, 2004, pp41 - 57, [Prendergast, PJ], Book Chapter, PUBLISHED
Prendergast, PJ, Life and Limb: The Bioengineering of Prostheses and Implants (R.I.A. Parsons Medal Lecture), Dublin, Trinity College Dublin, 2003, 30pp, Book, PUBLISHED
What a piece of work is a man in, editor(s)EP O'Neill , New Irish Writing in Science, Dublin, Trinity College Dublin, 2003, [Prendergast, PJ], Book Chapter, SUBMITTED

  

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Award Date
Wartenweiler Memorial Lecture, International Society of Biomechanics 2009
Elected Member of the Royal Irish Academy 2008
President Elect of European Alliance of Biomedical Engineering Societies 2006
Parsons Medal in Engineering Science, Royal Irish Academy 2003
President, European Society of Biomechanics 2002-04
Elected to Fellowship of Trinity College Dublin 1998
President, Section of Bioengineering, Royal Academy of Medicine in Ireland 1998-00
European Society of Biomechanics Research Award (S.M. Perren Award) 1996
Fellow, Irish Academy of Engineering 2011
Honorary Fellow, Oriel College Oxford 2012
Fellow, Royal Academy of Engineering (International) 2013
Chief Guest and Speaker at the 28th Convocation Address, Thapar University, Patiala, India 2014
Honorary Fellow, Anatomical Society 2016
Honorary Member, European Society of Biomechanics 2018
Honorary Member, St Peter's College Past Pupils' Union 2023
His research interests are in biomechanics and implant design, and in tissue engineering and mechanobiology.