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Dr. John Walsh

Associate Professor (Pharmacy)
25/6/7 WESTLAND ROW

 jjwalsh@tcd.ie

 3531896 2806


Research Tags

  ALLERGY   ASSAY   BASOPHILS   DRUG DISCOVERY   ENDOTHELIAL CELLS   HISTAMINE   MALARIA   MAST-CELLS   NATURAL PRODUCT SYNTHESIS   PROTEASES   VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)

Research Projects

 Development of Dual Inhibitors of Tumour Angiogenesis/Vasculature
 Pre-clinical Development of Novel Anti-allergic Compounds
 Design of Tumour Homing Vasculature Targeting Agents
 Design of Hybrid-based Tumour Homing Anti-angiogenesis Agents
 Studies on Novel Mast Cell Stabilising Compounds

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Representations

Details Date
Ireland representative on Committee 13b of the European Pharmacopoeia, Strasbourg. 2016

Memberships

Membership of Professional Institutions, Associations, Societies

Details Date From Date To
Phytochemical Society of Europe 1998 to date
European Histamine Research Society 2002 to date
Quanxiang Yan, Tao Zhang, Christine O'Connor, James W. Barlow, John Walsh, Gaia Scalabrino, Feng Xu, Helen Sheridan, The biological responses of vitamin K2: A comprehensive review, Food Science & Nutrition, 00, 2023, p1 - 23, Notes: [https://doi.org/10.1002/fsn3.3213], Journal Article, PUBLISHED
Anwar N, Khan A, Shah M​, Walsh JJ, Saleem S, Anwar Z, Aslam S, Irshad M., Hybridization of green synthesized silver nanoparticles with poly(ethylene glycol) methacrylate and their biomedical applications., PeerJ , (10), 2022, p1 - 28, Journal Article, PUBLISHED
Collyer, Samuel E., Gary D. Stack, and John J. Walsh, Selective Delivery of Clinically Approved Tubulin Binding Agents through Covalent Conjugation to an Active Targeting Moiety, CURRENT MEDICINAL CHEMISTRY, 29, (31), 2022, p5179 - 5211, Notes: [DOI:10.2174/0929867329666220401105929], Journal Article, PUBLISHED
Ryan TJ, Ryder SA, D'Arcy DM, Quigley JM, Ng NN, Ong WQ, Tey ZH, O'Dwyer M, Walsh JJ., Development of Professional Attributes through Integration of Science and Practice at First-Year Pharmacy Level, Pharmacy, 2021, Journal Article, PUBLISHED  DOI
Ijaz S, Shoaib Khan HM, Anwar Z, Talbot B, Walsh JJ, HPLC profiling of Mimosa pudica polyphenols and their non-invasive biophysical investigations for anti-dermatoheliotic and skin reinstating potential, Biomedicine & Pharmacotherapy, 109, 2019, p865 - 875, Journal Article, PUBLISHED  TARA - Full Text  DOI
Ryan, T.J.; Grimes, T.; Henman, M.C.; Sheachnasaigh, E.N.; O'Dwyer, M.; Roche, C.; Ryder, S.A.; Sasse, A.; Walsh, J.J. & D'Arcy, D.M, Design and Implementation of an Integrated Competency-Focused Pharmacy Programme: A Case Report., Pharmacy, 7, (3), 2019, pdoi.org/10.3390/pharmacy703012 , Notes: [doi.org/10.3390/pharmacy7030121], Journal Article, PUBLISHED  DOI
Zeeshan Anwar, Synthesis of Tubulin Inhibitors with Variable Molecular Hinges for the Attachment of Aminopeptidase N Targeting Moieties, Trinity College Dublin, 2019, Notes: [PhD], Thesis, PUBLISHED
Denise Ropero, Phytochemical studies on Choisya x dewitteana 'Aztec Pearl', 2018, Notes: [PhD], Thesis, PUBLISHED
Zhang T, Finn D.F, Barlow J.W, Walsh J.J, Mast cell stabilisers, European Journal of Pharmacology, 778, 2016, p158 - 168, Notes: [Cited By :8 Export Date: 27 January 2017], Journal Article, PUBLISHED  DOI  URL
Linker technologies and release mechanisms for antibody-drug conjugates in, editor(s)Professor Norbert Sewald , Optimizing antibody-drug conjugates for targeted delivery of therapeutics, Future press, 2015, pp40 - 55, [John J. Walsh and Gary D. Stack ], Book Chapter, PUBLISHED  DOI
  

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O'Dwyer M, Ryan T, Ryder S, D'Arcy DM, Walsh J. , Innovative Development and Evaluation of Professional Attributes through Integration of Science and Practice at First Year Pharmacy Level , Irish Network of Healthcare Educators Conference, TBSI, Trinity College Dublin, Dublin, Ireland , February 2020, 2020, Oral Presentation, PRESENTED
CG Clerkin, M Matzinger, MA Selo, BN Talbot, JJ Walsh, C Ehrhardt, Nucleophilic substitution reactions of ergothioneine might be a novel xenobiotic deactivation mechanism, 32nd Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 29/11-01/12/2017, 2017, Oral Presentation, PRESENTED
C Ehrhardt, S Nickel, MA Selo, CG Clerkin, JJ Salomon, B Talbot, JJ Walsh, OCTN1-mediated ergothioneine uptake protects lung epithelial cells from tobacco smoke-induced damage, FASEB J, Experimental Biology Meeting 2015, Boston, MA, 28/03-01/04/2015, 29, 2015, pp970.7 , Meeting Abstract, PUBLISHED

  

Awards and Honours

Award Date
Henkel Award (Organic Chemistry)

Research Interests

Description Of Research Interests

Drug discovery, Assay development, Tumour Angiogenesis, Tumour Vasculature, Endothelial cells, Tubulin, Proteases, Integrins, Vascular Endothelial Growth Factor, Allergies, Mast cells, Basophils, Histamine, Malaria, Natural Products, Herbal Medicinal Products. Research students supervised: PhD graduates: Dr James Barlow (Jan 2003); Dr Emmet McCormack (Apr 2003); Dr Richard Shah (Apr 2003); Dr Adam Byrne (Jun 2007); Dr Gillian Hudson (Jun 2007); Dr Martina White (Sept 2008); Dr Tao Zhang (February 2010); Dr Orla Woods, (December 2010); Dr Paul O'Byrne (Conjoint with JG), (December 2010); Dr Deirdre Finn, (October 2011), Dr Elaine Breen (December 2012), Dr Ekatherine Prokopiou (Conjoint with SR) (January 2013), Dr Gary Stack (July 2013), Dr Adrian Coogan (August 2013). MSc students supervised: Sharon Butterly Jun 1998 (Conjoint with NF); Aengus McHugh (Apr 2007); William Casey, (November 2010); Miriam Holohan (October 2011).