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Dr. John Walsh

Associate Professor (Pharmacy)
25/6/7 WESTLAND ROW
      
Profile Photo

Dr. John Walsh

Associate Professor (Pharmacy)
25/6/7 WESTLAND ROW

 jjwalsh@tcd.ie

 3531896 2806


  ALLERGY   ASSAY   BASOPHILS   DRUG DISCOVERY   ENDOTHELIAL CELLS   HISTAMINE   MALARIA   MAST-CELLS   NATURAL PRODUCT SYNTHESIS   PROTEASES   VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)
Project Title
 Development of Dual Inhibitors of Tumour Angiogenesis/Vasculature
From
Oct 2008
To
Sept 2011
Summary
Funding Agency
Enterprise Ireland
Programme
CFTD Commercialisation Fund Technology Development Phase
Project Type
Cancer
Person Months
96
Project Title
 Pre-clinical Development of Novel Anti-allergic Compounds
From
Oct 2004
To
Mar 2009
Summary
Funding Agency
Enterprise Ireland
Programme
EI-CFTD/04/115: Commercialisation Fund Technology Development Phase
Project Type
Allergy Research
Person Months
120
Project Title
 Design of Tumour Homing Vasculature Targeting Agents
From
01-10-2008
To
30-09-2011
Summary
Funding Agency
Irish Research Council for Science Engineering and Technology
Programme
EMBARK Postgraduate Scholarship Scheme 2008
Project Type
Cancer
Person Months
36
Project Title
 Design of Hybrid-based Tumour Homing Anti-angiogenesis Agents
From
01-10-2008
To
30-09-2011
Summary
Funding Agency
Irish Research Council for Science Engineering and Technology
Programme
EMBARK Postgraduate Scholarship Scheme 2008
Project Type
Cancer
Person Months
36
Project Title
 Studies on Novel Mast Cell Stabilising Compounds
From
01-10-2008
To
30-09-2009
Summary
Funding Agency
Irish Research Council For Science Engineering and Technology
Programme
EMBARK Postgraduate Scholarship Scheme 2008
Project Type
Allergy
Person Months
12

Page 1 of 2
Details Date
Ireland representative on Committee 13b of the European Pharmacopoeia, Strasbourg. 2016
Details Date From Date To
Phytochemical Society of Europe 1998 to date
European Histamine Research Society 2002 to date
Quanxiang Yan, Tao Zhang, Christine O'Connor, James W. Barlow, John Walsh, Gaia Scalabrino, Feng Xu, Helen Sheridan, The biological responses of vitamin K2: A comprehensive review, Food Science & Nutrition, 00, 2023, p1 - 23, Notes: [https://doi.org/10.1002/fsn3.3213], Journal Article, PUBLISHED
MJ Lyons, C Ehrhardt, JJ Walsh, Orellanine: From fungal origins to a future cancer treatment, J Nat Prod, 86, (6), 2023, p620-1631 , Review Article, PUBLISHED  URL
Anwar N, Khan A, Shah M​, Walsh JJ, Saleem S, Anwar Z, Aslam S, Irshad M., Hybridization of green synthesized silver nanoparticles with poly(ethylene glycol) methacrylate and their biomedical applications., PeerJ , (10), 2022, p1 - 28, Journal Article, PUBLISHED
Collyer, Samuel E., Gary D. Stack, and John J. Walsh, Selective Delivery of Clinically Approved Tubulin Binding Agents through Covalent Conjugation to an Active Targeting Moiety, CURRENT MEDICINAL CHEMISTRY, 29, (31), 2022, p5179 - 5211, Notes: [DOI:10.2174/0929867329666220401105929], Journal Article, PUBLISHED
Ryan TJ, Ryder SA, D'Arcy DM, Quigley JM, Ng NN, Ong WQ, Tey ZH, O'Dwyer M, Walsh JJ., Development of Professional Attributes through Integration of Science and Practice at First-Year Pharmacy Level, Pharmacy, 2021, Journal Article, PUBLISHED  DOI
Ijaz S, Shoaib Khan HM, Anwar Z, Talbot B, Walsh JJ, HPLC profiling of Mimosa pudica polyphenols and their non-invasive biophysical investigations for anti-dermatoheliotic and skin reinstating potential, Biomedicine & Pharmacotherapy, 109, 2019, p865 - 875, Journal Article, PUBLISHED  TARA - Full Text  DOI
Ryan, T.J.; Grimes, T.; Henman, M.C.; Sheachnasaigh, E.N.; O'Dwyer, M.; Roche, C.; Ryder, S.A.; Sasse, A.; Walsh, J.J. & D'Arcy, D.M, Design and Implementation of an Integrated Competency-Focused Pharmacy Programme: A Case Report., Pharmacy, 7, (3), 2019, pdoi.org/10.3390/pharmacy703012 , Notes: [doi.org/10.3390/pharmacy7030121], Journal Article, PUBLISHED  DOI
Zeeshan Anwar, Synthesis of Tubulin Inhibitors with Variable Molecular Hinges for the Attachment of Aminopeptidase N Targeting Moieties, Trinity College Dublin, 2019, Notes: [PhD], Thesis, PUBLISHED
Denise Ropero, Phytochemical studies on Choisya x dewitteana 'Aztec Pearl', 2018, Notes: [PhD], Thesis, PUBLISHED
Zhang T, Finn D.F, Barlow J.W, Walsh J.J, Mast cell stabilisers, European Journal of Pharmacology, 778, 2016, p158 - 168, Notes: [Cited By :8 Export Date: 27 January 2017], Journal Article, PUBLISHED  DOI  URL
  

Page 1 of 7
O'Dwyer M, Ryan T, Ryder S, D'Arcy DM, Walsh J. , Innovative Development and Evaluation of Professional Attributes through Integration of Science and Practice at First Year Pharmacy Level , Irish Network of Healthcare Educators Conference, TBSI, Trinity College Dublin, Dublin, Ireland , February 2020, 2020, Oral Presentation, PRESENTED
CG Clerkin, M Matzinger, MA Selo, BN Talbot, JJ Walsh, C Ehrhardt, Nucleophilic substitution reactions of ergothioneine might be a novel xenobiotic deactivation mechanism, 32nd Annual Meeting of the Japanese Society for the Study of Xenobiotics, Tokyo, Japan, 29/11-01/12/2017, 2017, Oral Presentation, PRESENTED
C Ehrhardt, S Nickel, MA Selo, CG Clerkin, JJ Salomon, B Talbot, JJ Walsh, OCTN1-mediated ergothioneine uptake protects lung epithelial cells from tobacco smoke-induced damage, FASEB J, Experimental Biology Meeting 2015, Boston, MA, 28/03-01/04/2015, 29, 2015, pp970.7 , Meeting Abstract, PUBLISHED

  


Award Date
Henkel Award (Organic Chemistry)
Drug discovery, Assay development, Tumour Angiogenesis, Tumour Vasculature, Endothelial cells, Tubulin, Proteases, Integrins, Vascular Endothelial Growth Factor, Allergies, Mast cells, Basophils, Histamine, Malaria, Natural Products, Herbal Medicinal Products. Research students supervised: PhD graduates: Dr James Barlow (Jan 2003); Dr Emmet McCormack (Apr 2003); Dr Richard Shah (Apr 2003); Dr Adam Byrne (Jun 2007); Dr Gillian Hudson (Jun 2007); Dr Martina White (Sept 2008); Dr Tao Zhang (February 2010); Dr Orla Woods, (December 2010); Dr Paul O'Byrne (Conjoint with JG), (December 2010); Dr Deirdre Finn, (October 2011), Dr Elaine Breen (December 2012), Dr Ekatherine Prokopiou (Conjoint with SR) (January 2013), Dr Gary Stack (July 2013), Dr Adrian Coogan (August 2013). MSc students supervised: Sharon Butterly Jun 1998 (Conjoint with NF); Aengus McHugh (Apr 2007); William Casey, (November 2010); Miriam Holohan (October 2011).