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Dr. Lidia Tajber

Associate Professor (Pharmacy)
25/6/7 WESTLAND ROW


Lidia is currently employed as an Associate Professor in Pharmaceutics and Pharmaceutical Technology in the School of Pharmacy and Pharmaceutical Sciences. She first gained M. Pharm. degree from Medical University of Silesia, Katowice, Poland (with first class honours, best in class) and then pursued her Ph.D. degree in the School of Pharmacy, Trinity College Dublin (completed in 2005). She holds a postgraduate diploma in quality improvement and completed "Research leaders" training. Lidia has published 76 high quality peer-review papers and contributed to numerous international conference presentations. Her current h-index is 25. She is also a co-inventor on a number of patent applications including "A method of producing porous microparticles" and "A polymeric nanoparticle". In addition to being an active researcher, she contributes to undergraduate (Pharmaceutics and Pharmaceutical Technology module) and postgraduate (Preformulation, Formulation and Advanced Drug Delivery modules) teaching. She is part of the coordinating team for the MSc in Pharmaceutical Sciences course. Lidia's research activities fit with national policy objectives supporting the development and production of a highly educated and relevant workforce in demand by the pharmaceutical industry. She and her team have successfully participated in collaborative, multidisciplinary and industry-led research consortia (IDDN, SSPC, H2020 RISE) leading to high impact research, leveraging international funding and attracting talented people to Ireland. The ultimate objective of her work is to advance the pharmaceutical product design and manufacture to benefit the general public and enhance the quality of health.
  Amorphous Materials   Chemical Physics   Composite materials   Computer modelling of pharmaceutical systems   Crystal engineering   DENDRIMERS   Drug Delivery Systems   Hydrogen bonding   LIQUID-CRYSTALLINE PROPERTIES   Nanotechnology   Pharmaceutical co-crystals   Pharmaceutical salts   Physical Chemistry   POLYMER   Polymers   POLYMORPHISM   Porous particles   Respiratory System   Spectroscopy   SPRAY DRYING   Thermal Analysis
 Synthesis and Solid State Pharmaceutical Centre
 TRANS-INT
 Solid State Pharmaceutical Cluster
 Active pharmaceutical ingredients as ionic liquids: significance of protonics and functional profiling for the design of effective medicines
 Irish Drug Delivery Network

Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
German Medium Basic Basic
Polish Fluent Fluent Fluent
Russian Fluent Medium Fluent
Details Date From Date To
American Chemical Society 2013
American Association of Pharmaceutical Scientists 2007
Controlled Release Society 2008
APV (International Association for Pharmaceutical Technology) 2017
Knapik-Kowalczuk J, Wojnarowska Z, Chmiel K, Rams-Baron M, Tajber L, Paluch M., Can Storage Time Improve the Physical Stability of Amorphous Pharmaceuticals with Tautomerization Ability Exposed to Compression? The Case of a Chloramphenicol Drug., Molecular Pharmaceutics, 15, (5), 2018, p1928 - 1940, Journal Article, PUBLISHED  DOI
McComiskey KPM, Mugheirbi NA, Stapleton J, Tajber L., In Situ Monitoring of Nanoparticle Formation: Antisolvent Precipitation of Azole Anti-fungal Drugs., International Journal of Pharmaceutics, 543, (1-2), 2018, p201 - 213, Journal Article, PUBLISHED  DOI
Inkielewicz-Stepniak I, Tajber L, Behan G, Zhang H, Radomski MW, Medina C, Santos-Martinez MJ, The Role of Mucin in the Toxicological Impact of Polystyrene Nanoparticles, Materials, 11, (5), 2018, p1 - 12, Journal Article, PUBLISHED  DOI
Sladek S, Kearney C, Crean D, Brama PAJ , Tajber L, Fawcett K, Labberte MC, Leggett B, Brayden DJ, Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation, Drug Delivery and Translational Research, 2018, p1 - 15, Journal Article, IN_PRESS  DOI
McComiskey K, Tajber L, Comparison of particle size methodology and assessment of nanoparticle tracking analysis (NTA) as a tool for live monitoring of crystallisation pathways, European Journal of Pharmaceutics and Biopharmaceutics, 130, 2018, p314 - 326, Journal Article, PUBLISHED
Borges VRA, Tavares M, Silva JH, Tajber L, Boylan F, Ribeiro A, Nasciuti LE, Cabral L, Sousa VP, Development and characterization of poly(lactic-co-glycolic) acid nanoparticles loaded with copaiba oleoresin, Pharmaceutical Development and Technology , 23, (4), 2018, p343 - 350, Journal Article, PUBLISHED  DOI
Mugheirbi N, O'Connell P, Serrano D, Healy AM, Taylor L, Tajber L, A comparative study on the performance of inert and functionalized spheres coated with solid dispersions made of two structurally related antifungal drugs, Molecular Pharmaceutics, 14, 2017, p3718 - 3728, Journal Article, PUBLISHED  TARA - Full Text  DOI
Umerska A, Corrigan OI, Tajber L, Design of chondroitin sulfate-based polyelectrolyte nanoplexes: Formation of nanocarriers with chitosan and a case study of salmon calcitonin, Carbohydrate Polymers, 156, 2017, p276 - 284, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Mesallati H, Umerska A, Paluch KJ, Tajber L, Amorphous polymeric drug salts as ionic solid dispersion forms of ciprofloxacin, Molecular Pharmaceutics, 14, 2017, p2209 - 2223, Journal Article, PUBLISHED  TARA - Full Text  DOI
Dul M, Paluch KJ, Healy AM, Sasse A, Tajber L, Optimisation of the self-assembly process: production of stable, alginate-based polyelectrolyte nanocomplexes with protamine, Journal of Nanoparticle Research, 19, (6), 2017, p221 - 231, Journal Article, PUBLISHED  TARA - Full Text  DOI
  

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Umerska A, Tajber L, Polyelectrolyte complexes as nanoparticulate drug delivery systems, European Pharmaceutical Review, 20, (3), 2015, p36-40 , Notes: [Invited review], Journal Article, PUBLISHED

  

Award Date
Trinity College Postgraduate Award 2001
Distinction for the M. Sc. thesis in the Master's Degree Dissertations Competition for Faculties of Pharmacy organised by Polish Pharmaceutical Society and Medical Universities 2001
First prize for the M.Sc. thesis in the Interdepartmental Master's Degree Dissertations Competition 2000
Prize from the Czestochowa branch of the Polish Pharmaceutical Chamber for the grades achieved in university degree 2000
My research programme concentrates on the fundamental understanding of molecular interactions governing the properties and performance of pharmaceutical substances (actives and additives) at molecular, supramolecular and formulation (drug product) levels. More specifically, the research topics pursued by my group are: . Advancement of the physicochemical and biopharmaceutical properties of active pharmaceutical ingredients (APIs) by conversion into ionic liquids (anti-crystal engineering); development of oral solid formulations containing ionic liquids . Synthesis, phase characterisation and behaviour in formulation of alternative forms of APIs such as salts, cocrystals, amorphous materials, polymorphs and liquid crystals; construction of multi-phase diagrams for stability . Rational preformulation studies leading to quality solid-state formulations . Nanocrystal and polymeric nanoparticle formulation and characterisation methods My research efforts have been supported by Science Foundation Ireland (SFI), Enterprise Ireland, Irish Research Council as well as the European Union. I am involved in the Synthesis and Solid State Pharmaceuticals Centre (https://www.sspc.ie/ ) as a funded investigator. I was awarded a prestigious SFI Career Development Award in 2017 on the development of pharmaceutical ionic liquid forms and also currently serve as Director of Steering Committee in a H2020 RISE network "ORBIS" (Open Research Biopharmaceutical Internships Support (http://orbisproject.eu/ , awarded in 2017). I currently supervise a group of 8 researchers and host visiting ORBIS secondees from the pharmaceutical industry.