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Dr. Clair Gardiner

Professor (Biochemistry)


  IMMUNOLOGY
Details Date From Date To
British Society for Immunology
Irish Society for Immunology
Róisín M. Loftus, Nadine Assmann, Nidhi Kedia-Mehta, Katie O'Brien, Arianne Garcia, Conor Gillespie, Jens L. Hukelmann, Clair M. Gardiner, Katja Dettmer, Doreen A. Cantrell, Linda V. Sinclair, David K. Finlay, Amino acid-dependent cMyc signalling is essential for murine NK cell metabolic and functional responses, Nature Communications, Revised manuscript, (Under Review), 2018, Notes: [Manuscript revised to address reviewers comments and resubmitted], Journal Article, SUBMITTED
Zaiatz-Bittencourt, D.K. Finlay, C.M. Gardiner. , Canonical TGF signalling pathway represses human NK cell metabolism, Journal of Immunology, 200, (12), 2018, p3934 - 3941, Journal Article, PUBLISHED
Clair M. Gardiner and David K. Finlay, What Fuels Natural Killers? Metabolism and NK Cell Responses, Frontiers in Immunolobgy, 8, 2017, Review Article, PUBLISHED  TARA - Full Text  DOI
Gardiner C.M, Mills K.H.G, The cells that mediate innate immune memory and their functional significance in inflammatory and infectious diseases, Seminars in Immunology, 28, (4), 2016, p343-350 , Journal Article, PUBLISHED  DOI  URL
Fischer J, Weber AN, Böhm S, Dickhöfer S, El Maadidi S, Deichsel D, Knop V, Klinker H, Möller B, Rasenack J, Wang L, Sharma M, Hinrichsen H, Spengler U, Buggisch P, Sarrazin C, Pawlita M, Waterboer T, Wiese M, Probst-Müller E, Malinverni R, Bochud PY, Gardiner CM, O'Farrelly C, Berg T., Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection., Gut, 2016, pdoi: 10.1136/gutjnl-2015-31023 , Journal Article, PUBLISHED  DOI  URL
Brennan K, McSharry BP, Keating S, Petrasca A, O'Reilly VP, Keane J, Doherty DG, Gardiner CM, Human Natural Killer cell expression of ULBP2 is associated with a mature functional phenotype., Human immunology, 77, (10), 2016, p876-885 , Journal Article, PUBLISHED  DOI
Deac OM, Mills JL, Gardiner CM, Shane B, Quinn L, Midttun O, McCann A, Meyer K, Ueland PM, Fan R, Lu Z, Brody LC, Molloy AM, Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults, J Nutr, 146, (9), 2016, p1801 - 1806, Journal Article, PUBLISHED  DOI
Dunphy SE, Guinan KJ, Chorcora CN, Jayaraman J, Traherne JA, Trowsdale J, Pende D, Middleton D, Gardiner CM, 2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells., Genes and immunity, 16, (5), 2015, p301-10 , Journal Article, PUBLISHED
Keating SE, Ní Chorcora C, Dring MM, Stallings RL, O'Meara A, Gardiner CM, Increased frequencies of the killer immunoglobulin-like receptor genes KIR2DL2 and KIR2DS2 are associated with neuroblastoma., Tissue antigens, 86, (3), 2015, p172-7 , Journal Article, PUBLISHED
Dunphy SE, Sweeney CM, Kelly G, Tobin AM, Kirby B, Gardiner CM, Natural killer cells from psoriasis vulgaris patients have reduced levels of cytotoxicity associated degranulation and cytokine production., Clinical immunology (Orlando, Fla.), 2015, Journal Article, PUBLISHED
  

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Gardiner CM, Breakthroughs in understanding NK cell metabolism, Seminar Series, Stanford University, July, 2014, Prof. Peter Parham, Invited Talk, PRESENTED
Gardiner CM, Natural Killer cells in cancer, Seminar Series, NUI Maynooth, November, 2013, Prof. Paul Moynagh, Invited Talk, PUBLISHED